This web page was produced as an assignment for Genetics 564, an undergraduate course at the University of Wisconsin-Madison.
CNGA-3 Protein
The cyclic nucleotide-gated cation channel alpha - 3 (CNGA3) protein is encoded by the CNGA3 gene and is 694 amino acids in humans. [1] The protein plays a role in the functioning in the retina and more specifically with the cone receptors in the retina. Cyclic GMP can activate the CNGA3 protein which causes a cation channel to open and therefore cause a depolarization of the cone photoreceptors. [2]
This protein is also found in other species: for more information look at the protein homology and phylogeny pages.
This protein is also found in other species: for more information look at the protein homology and phylogeny pages.
Function:
The CNGA3 protein forms a subunit in the ion channels in cones that are essential for vision. This ion channel allows positive ions to flow into the cones in the dark and stops the flow when there is a light stimulus. This is demonstrated below.
The CNGA3 protein forms a subunit in the ion channels in cones that are essential for vision. This ion channel allows positive ions to flow into the cones in the dark and stops the flow when there is a light stimulus. This is demonstrated below.